Choosing a Byte Order when saving a tiff in Photoshop (CS/CS2/CS3/CS4/CS5)

When saving a file as a tiff in Photoshop, there are two choices for how you want the byte order saved: PC or Macintosh. Essentially, most modern computers and applications will open a TIFF saved in either format just fine. However, it’s best to stick with the operating system you’ll be using when you work with the file.